Network firewall rules are blocking outbound HTTP/HTTPS traffic from ServiceNow instance to the target host on the required ports. (high likelihood)
MID Server is offline, misconfigured, or not properly routing traffic when the REST message is configured to use a MID Server for connectivity. (high likelihood)
Target hostname or IP address is incorrect, misspelled, or the target service is down or moved to a different endpoint. (medium likelihood)
Proxy configuration issues preventing the ServiceNow instance from reaching external hosts through corporate proxy servers. (medium likelihood)
DNS resolution failure where the hostname cannot be resolved to an IP address from the ServiceNow instance or MID Server. (low likelihood)