getReference() method returned null because the referenced record does not exist or the reference field is empty, then attempting to call methods on the null result. (high likelihood)
GlideRecord query returned no results and next() was not checked before calling methods on the assumed record object. (high likelihood)
API object or ServiceNow class failed to instantiate properly due to missing parameters, invalid configuration, or insufficient privileges. (medium likelihood)
Variable or object was declared but never initialized, or was explicitly set to null/undefined before method call. (medium likelihood)
Asynchronous operation has not completed yet, leaving the object undefined when the method call executes. (low likelihood)